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McKesson Corporation MCK witnessed strong momentum in the year-to-date period. Shares of the company rallied 34.1% compared with 2.9% growth of the industryin the same period. The S&P 500 Composite has risen 24.5% during the same time frame.
With healthy fundamentals and strong growth opportunities, this Zacks Rank #3 (Hold) company appears to be a solid wealth creator for its investors at the moment.
Headquartered in San Francisco, CA, McKesson is a healthcare services and information technology company with two operating segments — Distribution Solutions and Technology Solutions. The first segment distributes branded and generic pharmaceutical drugs, along with other healthcare-related products, on a global basis. The second segment offers enterprise-wide clinical, patient care, financial, supply chain and strategic management software solutions.
Factors Favoring MCK’s Growth
The rally in MCK’s shares can be attributed to the strength of its robust U.S. Pharmaceutical business. This optimism, led by a solid second-quarter performance and increasing demand for healthcare, is expected to contribute further. However, weak pricing trends are concerning.
Investors seem optimistic regarding the updated earnings guidance. On its second-quarter 2025 earnings call, McKesson raised its adjusted earnings per share (EPS) guidance for fiscal 2025. It now expects adjusted EPS in the range of $32.40-$33.00 (previously expected $31.75-$32.55), which represents growth of 18-20% from the prior-year level. Revenues are expected to grow 15%-17% from the prior-year figure.
The company recorded a significant uptick in its overall top line during the second quarter. This growth was primarily driven by the U.S. Pharmaceutical segment and continued momentum in the Pharmaceutical segment, especially for specialty products and GLP-1 medications. MCK also recorded increased prescription volumes during the quarter.
International segment revenues also witnessed growth year over year. This was due to higher pharmaceutical distribution volumes in the Canadian business. Revenues in the Medical-Surgical Solutions segment were primarily driven by higher volumes of specialty pharmaceuticals, including vaccines in the primary care channel.
Investors also seem to be interested in the company’s recent strategic collaboration. This month, Ontada, a McKesson business, announced a strategic collaboration with Datavant, a health data platform, to include Ontada’s data in their health ecosystem. This collaboration aims to help life science companies quickly access Ontada’s real-world data.
Also, this month, InspiroGene, another MCK business, was selected by Vertex Pharmaceuticals Incorporated to expand commercial distribution options for CASGEVY. The availability of the FDA-approved drug is expected to significantly solidify McKesson’s foothold in the sickle cell disease treatment space.
Factor That May Offset the Gains for MCK
McKesson distributes generic pharmaceuticals, which are subject to price fluctuation. The Distribution Solutions segment had experienced weaker generic pharmaceutical pricing trends, which continue to persist. Continued volatility, unfavorable pricing trends, reimbursement of generic drugs and significant fluctuations in the nature, frequency and magnitude of generic pharmaceutical launches could affect McKesson.
Stocks to Consider
Some better-ranked stocks from the medical industry are Masimo MASI, AngioDynamics ANGO and Globus Medical GMED.
Masimo, sporting a Zacks Rank #1 (Strong Buy) at present, has an estimated growth rate of 10.4% for 2025. You can see the complete list of today’s Zacks #1 Rank stocks here.
MASI’s earnings surpassed estimates in each of the trailing four quarters, delivering an average surprise of 17.10%. Masimo’s shares have risen 37.2% year to date compared with the industry’s 6.7% growth.
AngioDynamics, carrying a Zacks Rank #2 (Buy) at present, has an estimated growth rate of 38.2% for 2025. ANGO’s earnings surpassed estimates in three of the trailing four quarters and missed once, delivering an average surprise of 31.71%.
AngioDynamics’ shares have lost 8.9% year to date against the industry’s 6.7% growth.
Globus Medical, carrying a Zacks Rank of 2 at present, has an estimated long-term growth rate of 12.7%. GMED’s earnings surpassed estimates in each of the trailing four quarters, delivering an average surprise of 12.1%. Its shares have risen 56.5% year to date compared with the industry’s 6.7% growth.
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McKesson Corporation’s MCK dedicated business focused on supporting the commercialization of cell and gene therapies, InspiroGene, has been selected by Vertex Pharmaceuticals Incorporated VRTX to expand commercial distribution options for CASGEVY. InspiroGene will partner with Vertex to expand distribution options for CASGEVY.
CASGEVY (exagamglogene autotemcel), the first CRISPR-based gene-editing therapy approved by the FDA, is indicated for the treatment of patients 12 years and above with sickle cell disease (SCD) with recurrent vaso-occlusive crises or transfusion-dependent β-thalassemia.
The availability of the FDA-approved drug is expected to significantly solidify McKesson’s foothold in the SCD treatment space.
Likely Trend of MCK Stock Following the News
Following the announcement on Nov. 14, shares of the company lost nearly 0.6% till yesterday.
Historically, the company has gained a high level of synergies from its various partnerships. Although the latest tie-up to expand commercial distribution options for VRTX’s CASGEVY is likely to be beneficial for MCK’s top-line growth going forward, the stock declined overall since the announcement despite a slight gain since Monday.
McKesson currently has a market capitalization of $78.85 billion. Its projected earnings per share growth of 18.5% is higher than the industry’s 7.5%. In the last reported quarter, MCK delivered an earnings surprise of 2.6%.
Rationale Behind McKesson’s Partnership
Per MCK’s management, SCD (a rare and life-threatening blood disorder) presents significant unmet needs. The partnership with Vertex is expected to enable to provide CASGEVY to patients in need, along with advancing future medicines. Management believes that by leveraging its extensive supply chain expertise and customer-centric approach, the company’s cell and gene therapy business will likely support innovative medicines advance from clinical development to commercial success.
InspiroGene will serve a dual role of leveraging Biologics By McKesson specialty pharmacy and McKesson Plasma & Biologics specialty distributor.
Industry Prospects in Favor of MCK
Per a report by Grand View Research, the global SCD treatment market was estimated at $2.75 billion in 2023 and is anticipated to witness a CAGR of 15.7% between 2024 and 2030. Factors like increasing disease awareness, advancements in medical research and technology, and a growing need for effective treatments are likely to drive the market.
Given the market potential, the latest partnership is expected to solidify McKesson’s foothold in the niche space.
McKesson’s Recent Partnerships
This month, McKesson’s oncology technology and insights business, Ontada, announced a strategic collaboration with health data platform, Datavant, to include Ontada’s data in their health ecosystem. The collaboration aims to help life science companies access Ontada’s real-world data, accelerating the discovery of critical insights that drive oncology innovation and improve the lives of cancer patients.
Last month, McKesson’s Ontada announced its collaboration with Microsoft to utilize Azure AI, including Azure OpenAI Service, to help efficiently process more than 150 million unstructured oncology document components. The collaboration is expected to significantly improve the ability for Ontada to extract crucial clinical information.
In September, McKesson’s independent specialty pharmacy specializing in oncology and rare disease areas, Biologics by McKesson, was selected by Servier as a limited specialty pharmacy provider for VORANIGO (vorasidenib) for the treatment of adult and pediatric patients 12 years and older with Grade 2 astrocytoma oroligodendroglioma with a susceptible isocitrate dehydrogenase-1 (IDH1) or isocitrate dehydrogenase-2 (IDH2) mutation following surgery including biopsy, sub-total resection, or gross total resection.
MCK’s Share Price Performance
Shares of the company have gained 35.8% in the past year compared with the industry’s 7.8% rise and the S&P 500's 30% growth.
McKesson’s Zacks Rank & Key Picks
Currently, MCK carries a Zacks Rank #3 (Hold).
A couple of better-ranked stocks in the broader medical space are Cardinal Health, Inc. CAH and Cencora, Inc. COR.
Cardinal Health, carrying a Zacks Rank #2 (Buy) at present, has an estimated long-term growth rate of 10.2%. CAH’s earnings surpassed estimates in each of the trailing four quarters, with the average surprise being 11.2%. You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
Cardinal Health’s shares have gained 13.7% compared with the industry’s 7.8% rise in the past year.
Cencora, carrying a Zacks Rank of 2 at present, has an estimated long-term growth rate of 10.1%. COR’s earnings surpassed estimates in each of the trailing four quarters, with the average being 6.9%.
Cencora has gained 21.8% against the industry’s 3.9% decline in the past year.
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