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Amgen Inc.‘s stock dropped over 7% on Tuesday following revelations about bone density loss in early trials of its experimental obesity drug MariTide, while CNBC’s Jim Cramer suggested the news could benefit rival Eli Lilly And Co .
What Happened: Previously undisclosed data from MariTide’s Phase 1 trial showed a 4% decrease in bone mineral density among participants receiving a 420mg dose during the 12-week multiple ascending dose study. According to Olivia Brayer of Cantor Fitzgerald, the information emerged from hidden tabs in extended data files related to the trial.
MariTide, positioned as a monthly alternative to weekly injections offered by competitors Novo Nordisk and Eli Lilly, operates through a different weight loss mechanism. The drug’s development has attracted significant attention due to its potential to disrupt the growing obesity treatment market.
“If Amgen has hidden bone risk data for its obesity drug, that’s huge news for Lilly which has become a pathetic stock of late,” Cramer wrote on X, formerly Twitter, announcing plans to discuss the implications at an upcoming meeting.
Jim Cramer@jimcramerNov 12, 2024If Amgen has hidden bone risk data for its obesity drug , that's huge news for Lilly which has become a pathetic stock of late. Club name.. will talk about it at Thursday's meeting
Why It Matters: Despite concerns, Cantor Fitzgerald maintained its Overweight rating on Amgen with a $405 price target. The firm acknowledged that while some bone density loss is expected during weight loss treatments, particularly with a suboptimal diet, the dose-dependent increase in bone density loss could raise red flags.
The analysis also revealed data about AMG 598, a predecessor molecule that Amgen may have been investigating to challenge assumptions about GIPR antagonism’s role in bone density loss.
Price Action: Eli Lilly stock closed at $818.86 on Tuesday, down 1.63% for the day, with a slight drop of 0.10% in after-hours trading. Despite this, the stock has seen a strong 38.27% increase year-to-date.
Meanwhile, Amgen ended the day at $298.84, down 7.14%. However, it saw a slight recovery after hours, rising 0.61%. Amgen's stock has gained 0.49% year-to-date, according to data from Benzinga Pro.
Read Next:
Image Via Shutterstock
Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
© 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
RISES OVER 1.6% AT IT’S HIGH FOR THE DAY AFTER EARLY DROP AND THE POWER INFLOW SIGNAL
Eli Lilly & Company today experienced a Power Inflow, a significant event for those who follow where smart money goes and value order flow analytics in their trading decisions.
Today, at 10:35 AM on November 12th, a significant trading signal occurred for Eli Lilly as it demonstrated a Power Inflow at a price of $816.14. This indicator is crucial for traders who want to know directionally where institutions and so-called "smart money" moves in the market. They see the value of utilizing order flow analytics to guide their trading decisions. The Power Inflow points to a possible uptrend in Lilly’s stock, marking a potential entry point for traders looking to capitalize on the expected upward movement. Traders with this signal closely watch for sustained momentum in Lilly’s stock price, interpreting this event as a bullish sign.
Signal description
Order flow analytics, aka transaction or market flow analysis, separate and study both the retail and institutional volume rate of orders (flow). It involves analyzing the flow of buy and sell orders, along with size, timing, and other associated characteristics and patterns, to gain insights and make more informed trading decisions. This particular indicator is interpreted as a bullish signal by active traders.
The Power Inflow occurs within the first two hours of the market open and generally signals the trend that helps gauge the stock’s overall direction, powered by institutional activity in the stock, for the remainder of the day.
By incorporating order flow analytics into their trading strategies, market participants can better interpret market conditions, identify trading opportunities, and potentially improve their trading performance. But let's not forget that while watching smart money flow can provide valuable insights, it is crucial to incorporate effective risk management strategies to protect capital and mitigate potential losses. Employing a consistent and effective risk management plan helps traders navigate the uncertainties of the market in a more controlled and calculated manner, increasing the likelihood of long-term success
If you want to stay updated on the latest options trades for LLY, Benzinga Pro gives you real-time options trades alerts.
Market News and Data brought to you by Benzinga APIs and include firms, like Finit USA, responsible for parts of the data within this article.
© 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
After Market Close UPDATE:
The price at the time of the Power Inflow was $816.14. The returns on the High price ($829.27) and Close price ($819.57) after the Power Inflow were respectively 1.6% and 0.4%. That is why it is important to have a trading plan that includes Profit Targets and Stop Losses that reflect your risk appetite.
Past Performance is Not Indicative of Future Results
© 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
US benchmark equity indexes retreated from Monday's all-time high closing levels as markets parsed comments by two Federal Reserve officials and awaited official consumer inflation data for October.
The Dow Jones Industrial Average fell 0.9% Tuesday to close at 43,911, while the S&P 500 dropped 0.3% to 5,984. The Nasdaq Composite lost 0.1% to 19,281.4. Materials saw the steepest decline among sectors, while communication services, technology, and consumer staples posted gains.
The US economy is in "a good place," while interest rates are off their recent peak and historic lows, Richmond Fed President Tom Barkin said. This puts policymakers in a position to "respond appropriately" irrespective of how the economy evolves, he added.
Separately, Minneapolis Fed President Neel Kashkari said the US monetary policy is "modestly restrictive," with short-term borrowing costs continuing to cool inflation and slow the economy, though not by much, Reuters reported.
On Thursday, the central bank's Federal Open Market Committee reduced its benchmark lending rate by 25 basis points, following a 50-basis-point cut in September.
The US 10-year yield jumped 12 basis points to 4.43% Tuesday, while the two-year rate advanced 8.6 basis points to 4.34%.
In economic news, US consumers' inflation expectations cooled in October, while labor market concerns eased, according to a survey by the New York Fed.
Official data are expected to show Wednesday that US consumer inflation rose 0.2% sequentially and 2.6% annually last month, according to a Bloomberg-compiled consensus.
Official producer prices data for October are scheduled to be released Thursday.
Small business optimism in the US rose more than projected in October, while the uncertainty index hit a record high, though that's likely to improve now that the presidential election is over, according to the National Federation of Independent Business' latest survey.
Donald Trump won the election last week, marking his return to the White House.
In company news, Mosaic shares dropped 7.7%, the steepest decline on the S&P 500, after its third-quarter financial results fell more than expected.
Amgen was the worst performer on the Dow and the Nasdaq, and among the worst on the S&P 500, down 7.1%.
Tyson Foods surpassed top- and bottom-line expectations for its fiscal fourth quarter and issued guidance implying a slight cooldown in sales in the new year amid ongoing uncertainties with its beef business. The company's shares rose 6.6%, the top gainer on the S&P 500.
Live Nation Entertainment shares gained 4.7%, among the best performers on the S&P 500. The company reported mixed third-quarter results late Monday and said it's seeing strong demand in the current quarter and into 2025 for its Ticketmaster sales segment.
West Texas Intermediate crude oil was little changed at $68.01 a barrel Tuesday. The Organization of the Petroleum Exporting Countries reduced its 2024 and 2025 global oil demand projections for the fourth straight month while raising its world economic growth forecasts.
Gold fell 0.4% to $2,607 per troy ounce, while silver rose 1% to $30.92 per ounce.
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